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Antitumor activity of spinasterol isolated from Pueraria roots

Abstract We purified phytoestrogens from Pueraria root (Pueraria Mirifica from Thailand and Pueraria lobata from Korea), which is used as a rejuvenating folk medicine in Thailand and China. Dried, powdered plant material was extracted with 100% ethanol and further separated by concentration, filtration, and thin layer silica gel chromatography. Using the fractions obtained during separation, […]

Effects of Pueraria Mirifica on Vascular Function of Ovariectomized Rabbits

Estrogen stimulates endothelial nitric oxide (NO) production and attenuates endothelial dysfunc-tion in ischemia/repurfusion and menopause. Recent studies have shown that phytoestrogens from dietary sources improve endothelial function and reduce cardiovascular risks. The Thai medicinal plant Pueraria Mirifica (PM) contains many potent phytoestrogens including miroestrol and deoxymiroestrol but no study on vascular function has been established. […]

Estrogen-like activities and cytotoxicity effects of Thai herbal medicines as natural ingredients in anti-ageing

The objective of the study was to search for the appropriate herbal extracts by comparative analysis of their estrogenic and cytotoxic activities. Some potentially estrogenic activity of herbal extracts  in the management of female disorder symptoms was investigated by E-screen assay. The extracts having a promising activity were further evaluated  in vitro  for their cytotoxic […]

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